Squamous Skin Cancer Biography
Source(google.com.pk)Squamous cell carcinoma (SCC) is an uncontrolled growth of abnormal cells arising in the squamous cells, which compose most of the skin’s upper layers (the epidermis). SCCs often look like scaly red patches, open sores, elevated growths with a central depression, or warts; they may crust or bleed. SCC is mainly caused by cumulative UV exposure over the course of a lifetime. It can become disfiguring and sometimes deadly if allowed to grow. An estimated 700,000 cases of SCC are diagnosed each year in the US, resulting in approximately 2,500 deaths.
SCCs may occur on all areas of the body including the mucous membranes and genitals, but are most common in areas frequently exposed to the sun, such as the rim of the ear, lower lip, face, bald scalp, neck, hands, arms and legs. Often the skin in these areas reveals telltale signs of sun damage, such as wrinkling, changes in pigmentation, and loss of elasticity.
The top layer of skin is the epidermis. The epidermis is very thin, averaging only about 1/100 of an inch thick. It protects the deeper layers of skin and the organs of the body from the environment.
Keratinocytes are the main cell type of the epidermis. These cells make an important protein called keratin that helps the skin protect the rest of the body.
The outer part of the epidermis is composed of flat keratinocytes called squamous cells that are constantly shed as new ones form. The lowest part of the epidermis is called the basal layer, and the keratinocytes here are called basal cells. These cells constantly divide to form new keratinocytes to replace the ones that wear off the skin’s surface.
Cells called melanocytes are also found in the epidermis. These skin cells make a brown pigment called melanin, which gives the skin its tan or brown color. It protects the deeper layers of the skin from some of the harmful effects of the sun. For most people, when skin is exposed to the sun, melanocytes make more of the pigment, causing the skin to tan or darken.
eparated from the deeper layers of skin by the basement membrane. This is an important structure because when a skin cancer becomes more advanced, it generally grows through this barrier and into the deeper layers.
Dermis
The middle layer of the skin is called the dermis. The dermis is much thicker than the epidermis. It contains hair follicles, sweat glands, blood vessels, and nerves that are held in place by a protein called collagen, which gives the skin its elasticity and strength.
Subcutis
The deepest layer of the skin is called the subcutis. The subcutis and the lowest part of the dermis form a network of collagen and fat cells. The subcutis helps the body conserve heat and has a shock-absorbing effect that helps protect the body’s organs from injury.
Types of skin cancer
Keratinocyte cancers
These are by far the most common skin cancers. They are called keratinocyte carcinomas or keratinocyte cancers because when seen under a microscope, their cells look like early forms of keratinocytes, the most common type of skin cell. Most keratinocyte cancers are basal cell carcinomas or squamous cell carcinomas.
Basal cell carcinoma
This is not only the most common type of skin cancer, but the most common type of cancer in humans. About 8 out of 10 skin cancers are basal cell carcinomas (also called basal cell cancers). When seen under a microscope, the cells in these cancers look like cells in the lowest layer of the epidermis, called the basal cell layer.
These cancers usually develop on sun-exposed areas, especially the head and neck. Basal cell carcinoma was once found almost entirely in middle-aged or older people. Now it is also being seen in younger people, probably because they are spending more time in the sun.
These cancers tend to grow slowly. It’s very rare for a basal cell cancer to spread to other parts of the body. But if a basal cell cancer is left untreated, it can grow into nearby areas and invade the bone or other tissues beneath the skin.
After treatment, basal cell carcinoma can recur (come back) in the same place on the skin. People who have had basal cell cancers are also more likely to get new ones elsewhere on the skin. As many as half of the people who are diagnosed with one basal cell cancer will develop a new skin cancer within 5 years.
Squamous cell carcinoma
About 2 out of 10 skin cancers are squamous cell carcinomas (also called squamous cell cancers). The cells in these cancers look like abnormal versions of the squamous cells seen in the outer layers of the skin.
These cancers commonly appear on sun-exposed areas of the body such as the face, ears, neck, lips, and backs of the hands. They can also develop in scars or chronic skin sores elsewhere. They sometimes start in actinic keratoses (described below). Less often, they form in the skin of the genital area.
Squamous cell cancers are more likely to grow into deeper layers of skin and spread to other parts of the body than basal cell cancers, although this is still uncommon.
Keratoacanthomas are dome-shaped tumors that are found on sun-exposed skin. They may start out growing quickly, but their growth usually slows down. Many keratoacanthomas shrink or even go away on their own over time without any treatment. But some continue to grow, and a few may even spread to other parts of the body. Their growth is often hard to predict, so many skin cancer experts consider them a type of squamous cell skin cancer and treat them as such.
Melanomas
These cancers develop from melanocytes, the pigment-making cells of the skin. Melanocytes can also form benign (non-cancerous) growths called moles. Melanoma and moles are discussed in our document Melanoma Skin Cancer.
Squamous Skin Cancer Skin Cancer Pictures Moles Symptoms Sings On Face Spots On Nose Photos Types Pics Wallpapers Pics
Squamous Skin Cancer Skin Cancer Pictures Moles Symptoms Sings On Face Spots On Nose Photos Types Pics Wallpapers Pics
Squamous Skin Cancer Skin Cancer Pictures Moles Symptoms Sings On Face Spots On Nose Photos Types Pics Wallpapers Pics
Squamous Skin Cancer Skin Cancer Pictures Moles Symptoms Sings On Face Spots On Nose Photos Types Pics Wallpapers Pics
Squamous Skin Cancer Skin Cancer Pictures Moles Symptoms Sings On Face Spots On Nose Photos Types Pics Wallpapers Pics
Squamous Skin Cancer Skin Cancer Pictures Moles Symptoms Sings On Face Spots On Nose Photos Types Pics Wallpapers Pics
Squamous Skin Cancer Skin Cancer Pictures Moles Symptoms Sings On Face Spots On Nose Photos Types Pics Wallpapers Pics
Squamous Skin Cancer Skin Cancer Pictures Moles Symptoms Sings On Face Spots On Nose Photos Types Pics Wallpapers Pics
Squamous Skin Cancer Skin Cancer Pictures Moles Symptoms Sings On Face Spots On Nose Photos Types Pics Wallpapers Pics
Squamous Skin Cancer Skin Cancer Pictures Moles Symptoms Sings On Face Spots On Nose Photos Types Pics Wallpapers Pics
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